Peptide Bond Resonance
The peptide bond exhibits resonance between a neutral form (C=O, C-N) and a zwitterionic form (C-O⁻, C=N⁺). This delocalization imparts partial double-bond character to the C-N lin...

Explore how these building blocks of life form the basis of all biological processes—from peptide bond formation to protein folding, and the implications in health and disease.
Dive deep into the fundamental principles that govern how amino acids form peptides, how proteins fold, and what happens when this process goes wrong.
Whether you're a student beginning to explore biochemistry, a researcher deepening your knowledge, or a professional staying current with the field, our comprehensive articles cover every aspect of amino acid and protein science.
Understand the 20 standard amino acids, their side chain properties, stereochemistry, and how they determine protein behavior.
Learn about resonance structures, bond geometry, and the mechanisms by which amino acids link to form polypeptide chains.
Explore thermodynamics, chaperone systems, and the energy landscape that guides proteins to their native conformations.
Discover how protein misfolding leads to amyloid formation, prion propagation, and neurodegenerative diseases.
From the fundamentals of amino acid chemistry to advanced topics in protein misfolding and therapeutic strategies.
Explore our comprehensive collection of articles covering everything from basic amino acid chemistry to advanced therapeutic strategies targeting protein aggregation kinetics.